When using Adobe, URLs in PDF documents do not open in a web browser when PolicyPak Browser Router (PPBR) is set as the default browser.
There is a Windows Defender Attack Surface Reduction Rule in place for Adobe:
Option 1: Remove the Attack Surface Reduction Rule for Adobe by deleting the rule highlighted below.
Option 2: (Recommended) Add exclusions for PolicyPak under “Exclude files and paths from Attack Surface Reduction Rules" policy.
Note: If you prefer you can block only the PPBR Agent executable instead of the entire PolicyPak folder: “C:\Program Files\PolicyPak\Browser Router\Client\PPBRAgent.exe”
Excluding the “C:\Program Files\PolicyPak” folder, (or if you prefer just “C:\Program Files\PolicyPak\Browser Router\Client\PPBRAgent.exe”) should be enough to resolve the issue with Adobe and Browser Router.
For a list of additional PolicyPak items that may need to be excluded please see the KB below: